Combination Radioimmunotherapy Approaches and Quantification of Immuno-PET
نویسندگان
چکیده
منابع مشابه
Combination Radioimmunotherapy Approaches and Quantification of Immuno-PET
Monoclonal antibodies (mAbs), which play a prominent role in cancer therapy, can interact with specific antigens on cancer cells, thereby enhancing the patient's immune response via various mechanisms, or mAbs can act against cell growth factors and, thereby, arrest the proliferation of tumor cells. Radionuclide-labeled mAbs, which are used in radioimmunotherapy (RIT), are effective for cancer ...
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Recent advances in molecular characterization of tumors have allowed identification of new molecular targets on tumor cells or biomarkers. In medical practice, the identification of these biomarkers slowly but surely becomes a prerequisite before any treatment decision, leading to the concept of personalized medicine. Immuno-positron emission tomography (PET) fits perfectly with this approach. ...
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The epidermal growth factor receptor (EGFR) is one of the most comprehensively studied molecular targets in head and neck squamous cell carcinoma (HNSCC). However, inherent and acquired resistance are serious problems and are responsible for limited clinical efficacy and tumor recurrence. In this study, we evaluated the feasibility of immuno-positron emission tomography (PET) imaging and radioi...
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ژورنال
عنوان ژورنال: Nuclear Medicine and Molecular Imaging
سال: 2016
ISSN: 1869-3474,1869-3482
DOI: 10.1007/s13139-015-0392-7